6-Chloro-4-methyl-2-pyridinecarboxylic acid ethyl ester

6-Chloro-4-methyl-2-pyridinecarboxylic acid ethyl ester - Names and Identifiers

Name	Ethyl6-chloro-4-methylpyridine-2-carboxylate
Synonyms	Ethyl 6-chloro-4-methylpicolinate Ethyl6-chloro-4-methylpyridine-2-carboxylate Ethyl 6-chloro-4-methylpyridine-2-carboxylate ethyl 6-chloro-4-methyl-pyridine-2-carboxylate Methyl 6-chloro-4-Methylpyridine-2-carboxylate 2-Pyridinecarboxylicacid,6-chloro-4-methyl-,ethylester 6-Chloro-4-methyl-2-pyridinecarboxylic acid ethyl ester 2-Pyridinecarboxylic acid, 6-chloro-4-methyl-, ethyl ester
CAS	1122090-50-9

6-Chloro-4-methyl-2-pyridinecarboxylic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C9H10ClNO2
Molar Mass	199.63
Boling Point	311.538°Cat760mmHg
Storage Condition	Room Temprature
Sensitive	Irritant
MDL	MFCD09838963

6-Chloro-4-methyl-2-pyridinecarboxylic acid ethyl ester - Introduction

Ethyl 6-chloro-4-methylpyridine-2-carboxylate, also known as metronidazole isopropyl acetate, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Density: approx. 1.11g/cm³
-Melting Point:-2°C
-Boiling point: 235°C
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide

Use:
Ethyl 6-chloro-4-methylpyridine-2-carboxylate has a variety of uses in chemical laboratories and industry, including:
-As an important synthetic intermediate of metronidazole compounds in the pharmaceutical field, it is used for the preparation of antibacterial drugs, etc.
-as a catalyst or solvent for chemical reactions.
-Used to study physical and chemical properties.

Preparation Method:
The preparation of ethyl 6-chloro-4-methylpyridine-2-carboxylate generally uses the following steps:
-Reaction of picoline with chloroacetic acid to obtain 6-chloro-4-picoline
-React 6-chloro-4-methylpyridine with methanol, and add an acid catalyst to obtain metronidazole ethyl acetate
-After purification and separation steps to obtain pure products

Safety Information:
-6-Chloro-4-methylpyridine-2-carboxylic acid ethyl ester is a compound commonly used in organic synthesis, but still has some safety risks.
-It is flammable and exposure to open flames, high heat or strong oxidants may cause a fire or explosion.
-Wear appropriate personal protective equipment such as chemical protective goggles, protective gloves and protective face masks during operation.
-Avoid inhaling its vapors, ensure that you operate in a well-ventilated area, or have an appropriate gas mask.
-Observe relevant safety regulations during use and storage, and keep away from flammable materials and strong oxidants.

Please note that for the preparation and use of chemicals, please strictly follow relevant regulations and safety operating procedures, and take appropriate protective measures.

Last Update：2024-04-09 15:17:50